Page 3 - MidWeek West - June 9, 2021

June 9, 2021 WEST OAHU VOICE 3
Cutting Edge Diabetic Foot Wound CareTreatment Study Now In Hawaii!
Do you have diabetes and a poorly healing wound on your foot for months or years?
ActiGraft® is a new FDA approved product that uses your own body’s healing process to close wounds.
Approved participants receive the treatment for free and are compensated for their participation in this important study.
No medical insurance required. For more information, or to schedule a free consultation, please contact: (808) 784-3050
MICROSCOPIC VIEW OF ACTIGRAFT
HOW ACTIGRAFT WORKS
RedDress’s ActiGraft® technology is revolutionizing the way we treat chronic wounds by managing each stage of the wound healing process. ActiGraft uses a patient’s own blood to create a whole blood clot tissue. This blood clot tissue is then applied to the wound, where it supports the natural healing processes of the body.
Hemostasis: The body works to stop the bleeding and start the healing process by activating a coagulation cascade. A fibrin blood clot forms that plugs severed blood vessels and fills in tissue discontinuity at the wound site.
Inflammation: During this phase, white blood cells and macrophages enter the wound to destroy bacteria and remove debris. The blood clot creates a fibrin scaffold that serves as a protective, provisional extracellular matrix (ECM) containing cytokines and growth factors that facilitate tissue repair.
Proliferation: The blood clot recruits endothelial cells and fibroblasts to synthesize a permanent ECM. The focus is filling and covering the wound.
Remodeling: The blood clot dries out and becomes a protective scab. Under the scab, tissue remodeling takes place undisturbed. The fibrin is replaced by fibronectin and hyaluronan, and the scab falls off to reveal a collagenous scar.
Case Example: Latrogenic Vascular Ulcer
100% Wound Reduction, Total Healing in 5 Weeks with 4 ActiGraft Applications
Patient Information
37 year old Female with diabetes mellitus | Right lateral malleolus | 8 week old ulcer, 16cm2
2 months of unsuccessful treatment with Standard of Care | Healing after 5 weeks with 4 ActiGraft Treatments
Initial observation Week 5
RECREATINGTHE NATURALWOUND HEALING ENVIRONMENT